Oxidative and non-oxidative active turnover of genomic methylcytosine in distinct pluripotent states
F. Spada, S. Schiffers, A. Kirchner, Y. Zhang, G. Arista, O. Kosmatchev, E. Korytiakova, R. Rahimoff, C. Ebert, T. Carell
The paper quantifies DNA methylation turnover in mouse pluripotent cells, revealing active oxidation-dependent and -independent processes in formative and primed states.
bioRxiv · Mar 9, 2020Cell Biology