Author

R. Ruza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

D. I. Stuart· 1 shared D. Zhou· 1 shared E. E. Fry· 1 shared H. M. E. Duyvesteyn· 1 shared J. Huo· 1 shared J. Radecke· 1 shared J. Ren· 1 shared L. Carrique· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

D. I. Stuart

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1 paper

Recent·Most cited

The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer

L. Carrique, H. M. E. Duyvesteyn, T. Malinaukas, Y. Zhao, J. Ren, D. Zhou, T. S. Walter, J. Radecke, J. Huo, R. Ruza, P. N. Shah, E. E. Fry, D. I. Stuart

The paper identifies a lipid-binding pocket in the SARS-CoV-2 Spike that stabilizes the prefusion trimer and shields neutralizing epitopes, suggesting it as a potential drug target.

bioRxiv · Aug 13, 2020 · PreprintMicrobiology