MicrobiologybioRxivPreprint
The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer
L. Carrique, H. M. E. Duyvesteyn, T. Malinaukas…·D. I. Stuart
The paper identifies a lipid-binding pocket in the SARS-CoV-2 Spike that stabilizes the prefusion trimer and shields neutralizing epitopes, suggesting it as a potential drug target.
DOI 10.1101/2020.08.13.249177