Cancer BiologybioRxiv
Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors
L. Goebel, T. Kirschner, S. Koska…·D. Rauh
This study designs and evaluates nucleotide-based covalent inhibitors for KRasG13C, showing they block nucleotide exchange and oncogenic signaling.
DOI 10.7554/elife.82184