A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice
A. Gheberemedhin, A. B. Salam, B. Adu-Addai, S. Noonan, R. Stratton, M. S. U. Ahmed, C. khantwal, G. Martin, L. Huixian, C. Andrews, K. Balasubramanyam, R. Udo, L. Henry, J. Jaynes, C. Yates
This study shows that RP-832c, a CD206-targeting peptide, reduces bleomycin-induced pulmonary fibrosis in mice by decreasing fibrosis markers and inflammatory cytokines, with efficacy comparable to Pirfenidone and better than Nintedanib.
bioRxiv · Jul 27, 2020 · PreprintPathology