Genetic analysis of the septal peptidoglycan synthase FtsWI complex supports a conserved activation mechanism for SEDS-bPBP complexes
S. Du, Y. Li, H. Gong, R. Zhan, S. Ouyang, K.-T. Park, J. Lutkenhaus
The paper identifies mutations in FtsW and FtsI that reveal the activation mechanism of the SEDS-bPBP complex FtsWI, showing it relies on an interaction between FtsW's ECL4 and FtsI's pedestal domain.
bioRxiv · Jan 21, 2021Microbiology