BiophysicsbioRxivPreprint
A mechanistic model for dynamics between CAR T cells and target cells captures features that determine killing profiles
Suriya Selvarajan, Kevin L. Scrudders, Kenneth Rodriguez-Lopez…·Shalini T. Low-Nam
The paper develops a mechanistic model to predict CAR T cell killing of tumor cells based on contact dynamics and extracts parameters that determine killing efficiency and tumor resilience.
DOI 10.1101/2025.06.24.661290