Molecular BiologyScience AdvancesPeer-reviewed
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription
Gary LeRoy, Ozgur Oksuz, Nicolas Descostes…·Danny Reinberg
The paper identifies LEDGF and HDGF2 as proteins that substitute for FACT in differentiated tissues to enable RNAPII to overcome nucleosome barriers during transcription.