GenomicsAlzheimer s Research & TherapyPeer-reviewed
A single- nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Jorge L. Del‐Aguila, Zeran Li, Umber Dube…·Oscar Harari
This study uses single-nuclei RNA-seq to compare cell proportions and gene expression in Mendelian and sporadic AD brains, identifying reduced excitatory neurons in a Mendelian carrier and proposing best practices for analysis.