Pharmacology & ToxicologyBritish Journal of CancerPeer-reviewed
Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
Yukimatsu Toh, Ling Wu, Jianghua Tu…·Qingyun J. Liu
This study develops and tests a camptothecin analog conjugate targeting LGR4/5/6 in CRC models, showing potent anti-tumor activity with minimal toxicity.
4 citations