MicrobiologybioRxivPreprint
ISG15-USP18 signaling restrains viperin-dependent metabolic antiviral restriction
Niklas L Kahler, Sefanit Rezene, Florine E. M. Scholte…·Soham Gupta
This study shows that ISG15-USP18 signaling limits viperin-dependent metabolic antiviral restriction by stabilizing USP18 and reducing viperin expression, thereby inhibiting viral replication.
DOI 10.64898/2026.03.13.711570