Compensatory evolution drives multidrug-resistant tuberculosis in Central Asia
M. Merker, M. Barbier, H. Cox, J.-P. Rasigade, S. Feuerriegel, T. A. Kohl, R. Diel, S. Borrell, S. Gagneux, V. Nikolayevskyy, S. Andres, U. Nübel, P. Supply, T. Wirth, S. Niemann
The paper investigates the evolutionary mechanisms behind multidrug-resistant tuberculosis in Central Asia, finding that compensatory mutations enhance resistance and transmission success.
bioRxiv · May 31, 2018Evolutionary Biology