ImmunologybioRxiv
Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response
E. McGowan, R. Rosenthal, A. Fiore-Gartland…·J. Hare
The paper uses computational models to identify immunogenic regions in the HIV proteome by analyzing HLA diversity and CD8 T-cell immune repertoires, offering a pipeline for vaccine design.
DOI 10.3389/fimmu.2021.609884