The evolution and mutational robustness of chromatin accessibility in Drosophila
S. Khodursky, E. B. Zheng, N. Svetec, S. M. Durkin, S. Benjamin, A. Gadau, X. Wu, L. Zhao
This study uses deep neural networks to analyze chromatin accessibility in Drosophila, showing sequence determinants are conserved and accessibility is mutationally robust yet malleable under selection.
bioRxiv · Jun 26, 2023 · PreprintEvolutionary Biology