Adjusted vascular contractility relies on integrity of progranulin pathway: Insights into mitochondrial function
S. Singh, A. Bruder-Nascimento, R. M. Costa, J. V. Alves, S. Bharathi, E. S. Goetzman, T. Bruder-Nascimento
This study shows that progranulin (PGRN) is essential for vascular contractility by regulating mitochondrial function, mitophagy, and redox signaling in vascular smooth muscle cells.
Journal of the American Heart Association · Feb 4, 2025Peer-reviewedPharmacology & Toxicology