heterotypic interaction promotes asymmetric division of human hematopoietic stem and progenitor cells
A. Candelas, B. Vianay, M. Gelin, L. Faivre, J. Larghero, L. Blanchoin, M. Thery, S. Brunet
This study shows that interaction with osteoblasts promotes asymmetric division of human HSPCs, leading to unequal inheritance of lysosomes and differentiation markers.
bioRxiv · Aug 31, 2023 · PreprintCell Biology