Collective interactions augment influenza A virus replication in a host-dependent manner
K. L. Phipps, K. Ganti, N. T. Jacobs, C.-Y. Lee, S. Carnacinni, M. C. White, M. Manandhar, B. E. Pickett, G. S. Tan, L. M. Ferreri, D. R. Perez, A. C. Lowen
The paper shows that influenza A virus requires collective interactions for replication in mammalian cells but not in avian cells, with the PA gene segment playing a key role.
bioRxiv · Mar 7, 2020Microbiology