OBSTRUCTIVE APNEAS IN A MOUSE MODEL OF CONGENITAL CENTRAL HYPOVENTILATION SYNDROME
A. Madani, G. Pitollat, E. Sizun, L. Cardoit, M. Ringot, T. BOURGEOIS, N. Ramanantsoa, C. Delclaux, s. dauger, M.-P. d'Ortho, M. Thoby-Brisson, J. GALLEGO, B. Matrot
This study shows that Phox2b27Ala/+ mice exhibit obstructive and mixed apneas, likely due to hypoglossal dysgenesis, in addition to central apneas and hypoventilation.
bioRxiv · Feb 15, 2021Physiology