PhysiologybioRxiv
OBSTRUCTIVE APNEAS IN A MOUSE MODEL OF CONGENITAL CENTRAL HYPOVENTILATION SYNDROME
A. Madani, G. Pitollat, E. Sizun…·B. Matrot
This study shows that Phox2b27Ala/+ mice exhibit obstructive and mixed apneas, likely due to hypoglossal dysgenesis, in addition to central apneas and hypoventilation.
DOI 10.1164/rccm.202104-0887oc