Combining an alarmin HMGN1 peptide with PD-L1 blockade facilitates stem-like CD8+ T cell expansion and results in robust antitumor effects
C.-Y. Chen, S. Ueha, Y. Ishiwata, S. Shichino, S. Yokochi, D. Yang, J. J. Oppenheim, H. Ogiwara, S. Deshimaru, Y. Kanno, T. Ogawa, S. Shibayama, K. Matsushima
This study combines an HMGN1 peptide with PD-L1 blockade to expand stem-like CD8+ T cells and enhance antitumor effects in mouse models.
bioRxiv · Dec 15, 2020Immunology