Work horse strain Clostridioides difficile 630Δerm is oblivious to its anaerobic lifestyle
D. Troitzsch, H. Zhang, S. Dittmann, D. Düsterhöft, A.-M. Michel, L. Jänsch, K. Riedel, J. M. Borrero-de Acuna, D. Jahn, S. Sievers
The study shows that the C. difficile strain 630Δerm has a mutation in PerR that causes oxidative stress response under anaerobic conditions, challenging its use as a model strain.
bioRxiv · Jan 7, 2020 · PreprintMicrobiology