Phagocyte-expressed glycosaminoglycans promote capture of alphaviruses from the blood circulation in a host species-specific manner.
S. E. Ander, M. G. Parks, B. J. Davenport, F. S. Li, A. Bosco-Lauth, K. S. Carpentier, C. Sun, C. J. Lucas, W. B. Klimstra, G. D. Ebel, T. E. Morrison
This study shows that phagocyte-expressed glycosaminoglycans mediate species-specific vascular clearance of alphaviruses, with some viruses being cleared faster than others.
bioRxiv · Aug 9, 2023Microbiology