Data-driven polymer model for mechanistic exploration of diploid genome organization
Y. Qi, A. Reyes, S. E. Johnstone, M. J. Aryee, B. E. Bernstein, B. Zhang
The paper introduces a data-driven polymer model to study diploid genome organization, validated against Hi-C data and showing chromosome positioning principles.
bioRxiv · Feb 27, 2020Biophysics