RNA-based vaccine demonstrates prophylactic efficacy against Mycobacterium tuberculosis challenge in a mouse model
S. E. Larsen, J. H. Erasmus, V. A. Reese, T. Pecor, J. Archer, A. P. Khandhar, F.-C. Hsu, S. G. Reed, S. L. Baldwin, R. N. Coler
This study evaluates two TB vaccine platforms in mice, showing both reduce bacterial burden, with RNA-based vaccines showing greater efficacy in combination immunization strategies.
bioRxiv · Feb 23, 2022 · PreprintImmunology