Author

J. Archer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Organism:non-human primate· 3 Approach:deep learning· 2 Organism:human· 2 Organism:rat· 2

Frequent Co-Authors

A. P. Khandhar· 4 shared D. H. Fuller· 4 shared D. W. Hawman· 4 shared H. Feldmann· 4 shared J. H. Erasmus· 4 shared S. Leventhal· 4 shared S. Randall· 4 shared K. Meade-White· 3 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

A. P. Khandhar

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Idioblasts accumulating anticancer alkaloids in Catharanthus roseus leaves are a unique cell type

J. G. Guedes, R. Ribeiro, I. Carqueijeiro, A. L. Guimaraes, C. Bispo, J. Archer, H. Azevedo, N. A. Fonseca, M. Sottomayor

The paper identifies Catharanthus roseus mesophyll idioblasts as a unique cell type with a distinct transcriptomic profile and high alkaloid accumulation, offering insights into improving anticancer alkaloid production.

bioRxiv · Feb 24, 2023 · PreprintPlant Biology

A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

M. A. O'Connor, D. W. Hawman, K. Meade-White, S. Leventhal, W. Song, S. Randall, J. Archer, T. B. Lewis, B. Brown, N. Iwayama, C. Ahrens, W. Garrison, S. Wangari, K. A. Guerriero, P. Hanley, , J. H. Erasmus

This study shows a replicon RNA vaccine provides durable protection against SARS-CoV-2 in nonhuman primates even after neutralizing antibodies decline.

bioRxiv · Aug 8, 2022 · PreprintImmunology

RNA-based vaccine demonstrates prophylactic efficacy against Mycobacterium tuberculosis challenge in a mouse model

S. E. Larsen, J. H. Erasmus, V. A. Reese, T. Pecor, J. Archer, A. P. Khandhar, F.-C. Hsu, S. G. Reed, S. L. Baldwin, R. N. Coler

This study evaluates two TB vaccine platforms in mice, showing both reduce bacterial burden, with RNA-based vaccines showing greater efficacy in combination immunization strategies.

bioRxiv · Feb 23, 2022 · PreprintImmunology

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

D. W. Hawman, K. Meade-White, C. Clancy, J. Archer, T. Hinkley, S. Leventhal, D. Rao, A. Stamper, M. Lewis, R. Rosenke, K. Krieger, S. Randall, A. P. Khandhar, L. Hao, T.-Y. Hsiang, , J. Erasmus

bioRxiv · Jan 31, 2022Microbiology

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern

D. W. Hawman, K. Meade-White, J. Archer, S. Leventhal, D. Wilson, C. Shaia, S. Randall, A. P. Khandhar, T.-Y. Hsiang, M. Gale, P. Berglund, D. H. Fuller, H. Feldmann, J. Erasmus

This study evaluates a replicating RNA vaccine against SARS-CoV-2 variants, showing protection from disease and reduced viral shedding after heterologous challenge.

bioRxiv · Dec 10, 2021Microbiology

Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi, Heligmosomoides polygyrus and Schistosoma mansoni

F. A. Partridge, C. J. Bataille, R. Forman, A. E. Marriott, J. Forde-Thomas, C. Häberli, R. L. Dinsdale, J. D. O'Sullivan, N. J. Willis, G. M. Wynne, H. Whiteland, J. Archer, A. Steven, J. D. Turner, J. Keiser, , D. B. Sattelle

The paper investigates the structure-activity relationship of dihydrobenzoxazepinone (DHB) compounds against various parasitic nematodes and trematodes, identifying key structural features for anthelmintic activity.

ACS Infectious Diseases · Apr 2, 2021Peer-reviewedPharmacology & Toxicology

Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates

J. H. Erasmus, A. P. Khandhar, A. C. Walls, E. A. Hemann, M. A. O'Connor, P. Murapa, J. Archer, S. Leventhal, J. Fuller, T. Lewis, K. E. Draves, S. Randall, K. A. Guerriero, M. S. Duthie, D. Carter, , D. H. Fuller

bioRxiv · May 28, 2020 · PreprintImmunology

Integrated technology platform for accelerated discovery of antiviral antibody therapeutics

P. Gilchuk, R. G. Bombardi, J. H. Erasmus, Q. Tan, R. S. Nargi, C. Soto, P. Abbink, T. J. Suscovich, L. A. Dunellin, A. Khandhar, J. Archer, J. Liang, M. E. Fouch, E. Davidson, B. Doranz, , R. H. Carnahan

This study develops an integrated platform to rapidly discover and validate potent antiviral human monoclonal antibodies against Zika virus.

bioRxiv · May 12, 2020Immunology