Cell BiologybioRxivPreprint
AICAR-mediated selection of karyotypically normal cells in Pallister-Killian syndrome patient-derived skin fibroblasts
E. Salzano, M. Kaur, A. M. Jacko…·K. Izumi
This study shows AICAR selectively eliminates isochromosome 12p cells in PKS fibroblasts, suggesting a potential therapeutic strategy for aneuploidy disorders.
DOI 10.1101/2022.01.27.478025