The β-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signalling
G. Sanchez, T. C. Incedal, J. P. Salcedo, P. O'Callaghan, S. Echeverry, P. M. Nguyen, B. Xie, S. Barg, J. Kreuger, T. Dandekar, O. Idevall-Hagren
The paper investigates Ca2+ dynamics in β-cell primary cilia and identifies GABA-B1 receptor-mediated paracrine signaling as a localized Ca2+ signaling mechanism.
bioRxiv · Aug 16, 2021Cell Biology