Sclerostin depletion induces inflammation in the bone marrow of mice
C. Donham, B. Chicana, A. G. Robling, A. Mohamed, S. Elizaldi, M. Chi, B. Freeman, A. Millan, D. Murguesh, G. G. Loots, J. O. Manilay
This study shows that sclerostin depletion in mice leads to myeloid-biased hematopoiesis and increased inflammation in the bone marrow.
bioRxiv · Nov 1, 2020Immunology