Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIP
A. Luebbers, M. Zhou, S. Eyles, M. Garcia-Marcos
This study identifies the molecular mechanism by which GINIP modulates GPCR signaling through conformational changes in its PHD domain, essential for Gi subunit binding and regulation of G-protein signaling.
bioRxiv · Apr 20, 2023Biochemistry