The Mutational Landscape of the SCAN-B Real-World Primary Breast Cancer Transcriptome
C. Brueffer, S. Gladchuk, C. Winter, J. Vallon-Christersson, C. Hegardt, J. Häkkinen, A. M. George, Y. Chen, A. Ehinger, C. Larsson, N. Loman, M. Malmberg, L. Ryden, A. Borg, L. H. Saal
The paper develops a pipeline to detect mutations from RNA-seq data in breast cancer and shows it can identify mutations in key genes and pathways in 86.8% of tumors.
bioRxiv · Jan 30, 2020Cancer Biology