MicrobiologybioRxivPreprint
Peptidyl tRNA hydrolase is required for robust prolyl-tRNA turnover in Mycobacterium tuberculosis
F. G. Tomasi, J. T. P. Schweber, S. Kimura…·E. J. Rubin
The paper develops Cu-tRNAseq to study peptidyl tRNA turnover in Mtb, finding Pth is essential for prolyl-tRNA recycling and identifies Pth as a potential TB therapeutic target.
DOI 10.1101/2022.11.15.516451