Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells
A. Armento, S. Honisch, V. Panagiotakopoulou, I. Sonntag, A. Jacob, E. Kilger, M. Deleidi, S. J. Clark, M. Ueffing
This study shows that loss of Complement Factor H in human RPE cells reduces antioxidant capacity and impairs energy metabolism, contributing to AMD pathogenesis.
bioRxiv · Jan 8, 2020Cell Biology