Cell BiologybioRxiv
Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells
A. Armento, S. Honisch, V. Panagiotakopoulou…·M. Ueffing
This study shows that loss of Complement Factor H in human RPE cells reduces antioxidant capacity and impairs energy metabolism, contributing to AMD pathogenesis.
DOI 10.1038/s41598-020-67292-z