A. Jacob

Structural Adaptation of Fungal Cell Wall in Hypersaline Environment

This study uses solid-state NMR to analyze the cell wall structure of Aspergillus sydowii under varying salinity conditions, revealing structural adaptations that enhance survival in hypersaline environments.

IRIS: Integrated Retinal Functionality in Image Sensors

The paper introduces IRIS, a neuromorphic image sensor technology that implements retinal-inspired motion computations for improved machine vision in dynamic environments.

Lytic Reactivation of the Kaposis sarcoma-associated herpesvirus (KSHV) is Accompanied by Major Nucleolar Alterations

This study shows that KSHV lytic reactivation causes nucleolar structural changes without affecting pre-rRNA levels or accumulation, suggesting rRNA processing continues but may be uncoupled.

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies

This study edits the PRR-βE1 region in HSPCs to suppress HbA and enhance HbF production, showing therapeutic benefits for β-hemoglobinopathies.

Sexual deprivation induces a CRF independent stress response and decreases resistance to stressors in Drosophila via a subpopulation of Neuropeptide F receptor-expressing neurons

This study shows that sexual deprivation in Drosophila increases stress sensitivity and arousal through a specific subset of Neuropeptide F receptor-expressing neurons, independent of CRF-like pathways.

Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells

This study shows that loss of Complement Factor H in human RPE cells reduces antioxidant capacity and impairs energy metabolism, contributing to AMD pathogenesis.