Directed evolution reveals the mechanism of HitRS signal transduction in Bacillus anthracis
E. P. Skaar, H. Pi, M. Chu, S. Ivan, C. Latario, A. Toth, S. Carlin, G. Hillebrand, H. Lin, J. Reppart, D. L. Stauff
This study uses genetic selections to uncover the molecular mechanism of the HitRS signal transduction system in Bacillus anthracis, identifying key residues and interactions essential for TCS function.
bioRxiv · Jul 3, 2020Biochemistry