ImmunologybioRxivPreprint
Cell state and transcription factor modulation during extended ex vivo CD8+ T-cell expansion.
Yuan Lui, Edward M. Jenkins, Emily Zhi Qing Ng…·Sumana Sharma
The paper uses bulk RNA-seq and single-cell RNA-seq data to study T-cell expansion and identifies FOSL1 as a transcription factor that promotes an effector phenotype, enhancing cancer-cell killing.
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