Antimalarial pantothenamide metabolites target acetyl-CoA synthesis in Plasmodium falciparum
J. Schalkwijk, E. L. Allman, P. A. Jansen, L. E. de Vries, S. Jackowski, P. N. Botman, C. A. Beuckens-Schortinghuis, K. M. Koolen, J. M. Bolscher, M. W. Vos, K. Miller, S. Reeves, H. Pett, G. Trevitt, S. Wittlin, , K. J. Dechering
Pantothenamides form antimetabolites that interfere with acetyl-CoA metabolism in the human malaria parasite Plasmodium falciparum.
bioRxiv · Feb 12, 2018Pharmacology & Toxicology