Trapped pore waters in the open proton channel HV1
D. Boytsov, S. Brescia, G. Chaves, S. Koefler, C. Hannesschlaeger, C. Siligan, N. Goessweiner-Mohr, B. Musset, P. Pohl
The paper investigates proton transport through HV1 channels, finding that water is trapped in the pore and that H+ conductance is reduced by removing a charged amino acid.
bioRxiv · May 9, 2022Biophysics