Cell BiologybioRxiv
Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients
L. Haupt, A. Maus, M. Tiburcy…·K. Streckfuss-Bömeke
This study develops a human iPSC-CM model of DOX-induced cardiac dysfunction in B-cell lymphoma patients with high-dose DOX treatment, showing increased susceptibility to DOX toxicity and impaired mechanical function.