Anti-citrullinated protein antibodies with diverse specificities ameliorate collagen antibody-induced arthritis in a time-dependent manner
A. M. Gomez, R. C. Brewer, J.-S. Moon, S. Acharya, S. Kongpachith, Q. Wang, S. Jahanbani, H. H. Wong, T. V. Lanz, Z. Z. Love, G. Min-Oo, A. Niedziela-Majka, W. H. Robinson
The study functionally characterizes ACPAs from RA patients and shows they reduce arthritis severity in a mouse model, with effects dependent on timing of treatment.
bioRxiv · Mar 8, 2023 · PreprintImmunology