Single-cell-resolved interspecies comparison identifies a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19
S. Peidli, G. Nouailles, E. Wyler, J. M. Adler, S. Kunder, A. Voss, J. Kazmierski, F. Pott, P. Pennitz, D. Postmus, L. G. Teixeira Alves, C. Goffinet, A. D. Gruber, N. Bluethgen, M. Witzenrath, , S. D. Praktiknjo
The paper compares single-cell RNA-seq data from hamster and human COVID-19 samples to identify a shared inflammatory axis and a neutrophil-endothelial program associated with severe disease.
bioRxiv · Aug 25, 2023Immunology