Author

S. Leclerc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

G. Andelfinger· 2 shared K. Fahy· 2 shared M. Vihinen-Ranta· 2 shared S. Kapishnikov· 2 shared S. Mattola· 2 shared V. Aho· 2 shared V. Ruokolainen· 2 shared A. Das· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

G. Andelfinger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Progression of herpesvirus infection remodels mitochondrial organization and metabolism

S. Leclerc, A. Gupta, V. Ruokolainen, J.-H. Chen, K. Kunnas, A. Ekman, H. Niskanen, I. Belevich, H. Vihinen, P. Turkki, A. Perez-Berna, S. Kapishnikov, E. Mäntylä, M. Harkiolaki, E. Dufour, , M. Vihinen-Ranta

This study shows how herpesvirus infection alters mitochondrial structure and metabolism during infection progression.

bioRxiv · Nov 16, 2023 · PreprintMicrobiology

Metabolic Reprogramming of the Neovascular Niche Promotes Regenerative Angiogenesis in Proliferative Retinopathy

G. Cagnone, S. Pundir, J. Sung-Kim, J. C. Rivera, T. Agnihotri, N.-R. Harvey, E. Heckel, C. Betus, M. X. Chen, A. Situ, P. Gaub, N. Kim, A. Das, S. Leclerc, F. Wunnemann, , J.-S. Joyal

This study shows that metabolic reprogramming in the neurovascular niche promotes regenerative angiogenesis in proliferative retinopathy by shifting metabolism from fatty acid oxidation to glycolysis.

bioRxiv · Nov 13, 2023Cell Biology

Clearance of defective muscle stem cells by senolytics reduces the expression of senescence-associated secretory phenotype and restores myogenesis in myotonic dystrophy type 1.

T. Conte, G. D. Bishop, Z. Orfi, I. Mokhtari, A. Deprez, M.-P. Roussel, I. Cote, O. Pellerito, D. Maggiorani, B. Benabdallah, S. Leclerc, L. Feulner, J. Mathieu, C. Gagnon, G. Andelfinger, , N. Dumont

This study identifies a senescent molecular signature in DM1 myogenic cells and shows that senolytics reduce SASP and restore myogenesis.

bioRxiv · Jun 22, 2022 · PreprintCell Biology

Parvovirus infection affects host cell nucleolar organization and ribosome biogenesis

M. Huttunen, S. Hakanen, V. Aho, S. Leclerc, A. Soenmez, S. Kapishnikov, A. Zannotti, V. Ruokolainen, K. Salokas, M. Varjosalo, L. Latonen, C. R. Parrish, K. Fahy, S. Mattola, D. L. Lafontaine, M. Vihinen-Ranta

This study investigates how canine parvovirus infection alters nucleolar structure and ribosome biogenesis using advanced imaging and biochemical techniques.

bioRxiv · Jun 7, 2022 · PreprintCell Biology