Author
H. Vihinen
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links7 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Peroxisomal tail-anchored proteins do not reach peroxisomes via ER, instead mitochondria can be involved.
T. Somborac, G. L. Bal, K. Fatima…·S. Konovalova
This study shows that peroxisomal tail-anchored proteins do not enter the ER but may use mitochondria as an intermediate for their targeting to peroxisomes.
DOI 10.1101/2023.05.22.541719 - Cell BiologybioRxivPreprint
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis
Y. Hazari, H. Urra, V. A. G. Lopez…·C. Hetz
This study shows that IRE1 regulates collagen secretion via P4HB, contributing to liver fibrosis in models of CCl4 and high fat diet.
DOI 10.1101/2023.05.02.538835 - Cell BiologybioRxiv
Global analysis of aging-related protein structural changes uncovers enzyme polymerization-based control of longevity
J. Paukstyte, R. M. Lopez Cabezas, Y. Feng…·J. Saarikangas
The paper identifies age-related protein structural changes in yeast and shows that inhibiting polymerization of glutamate synthase extends lifespan.
DOI 10.1016/j.molcel.2023.08.015 - Cell BiologybioRxiv
Seipin traps triacylglycerols to facilitate their nanoscale clustering in the ER membrane
X. Prasanna, V. T. Salo, S. Li…·E. Ikonen
This study shows seipin traps triacylglycerols in the ER membrane via its luminal hydrophobic helices, facilitating their nanoscale clustering and promoting TAG transfer to lipid droplets.
DOI 10.1371/journal.pbio.3000998 - Cell BiologybioRxiv
Myosin-X and talin modulate integrin activity at filopodia tips
M. Miihkinen, M. L. B. Grönloh, H. Vihinen…·G. Jacquemet
The paper identifies MYO10 and talin as key regulators of integrin activity in filopodia, proposing a two-step model for integrin activation.
DOI 10.1016/j.celrep.2021.109716 - ImmunologybioRxiv
B cells rapidly target antigen and surface-derived MHCII into peripheral degradative compartments.
S. Hernandez-Perez, M. Vainio, E. Kuokkanen…·P. Mattila
This study identifies specialized early peripheral acidic vesicles (eMIIC) in B cells that facilitate rapid antigen processing and MHCII peptide loading for immune response.