BiochemistrybioRxiv
X-Ray Structure and enzymatic study of a Bacterial NADPHoxidase highlight the activation mechanism of eukaryoticNOX
I. Petit-Hartlein, A. Vermot, M. Thepaut…·F. Fieschi
The paper presents crystal structures of SpNOX and its DH domain, revealing the activation mechanism of eukaryotic NOX by elucidating hydride transfer and flavin binding.
DOI 10.7554/elife.93759