AKT1 is Required for a Complete Palbociclib-induced Senescence Phenotype in BRAF-V600E-Driven Human Melanoma
A. L. Bayer, J. Pietruska, J. Farrell, S. McRee, P. Alcaide, P. W. Hinds
This study shows AKT1 is required for Palbociclib-induced senescence in BRAF-V600E melanoma cells, acting through NF-kB but not cGAS-STING.
bioRxiv · Dec 2, 2021Cancer Biology