Author

P. Alcaide

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. L. Bayer· 2 shared A. Poltorak· 1 shared A. Tai· 1 shared B. Xu· 1 shared C. Branche· 1 shared D. Lee· 1 shared E. E. Graves· 1 shared E. R. Reed· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. L. Bayer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

STING promotes homeostatic maintenance of tissues and confers longevity with aging

J. W. Hopkins, K. B. Sulka, M. Sawden, K. A. Carroll, R. D. Brown, S. C. Bunnell, A. Poltorak, P. Alcaide, A. Tai, E. R. Reed, S. Sharma

This study shows that STING signaling maintains tissue homeostasis and promotes longevity by regulating immune fingerprints and macrophage function during aging.

bioRxiv · Apr 4, 2024 · PreprintImmunology

A Novel Therapeutic Approach using CXCR3 Blockade to Treat Immune Checkpoint Inhibitor-mediated Myocarditis

Y. V. Huang, D. Lee, Y. Sun, H. Chou, B. Xu, Z. Lin, C. Branche, A. L. Bayer, S. Waliany, J. Neal, H. Wakelee, R. Witteles, P. Nguyen, E. E. Graves, P. Alcaide, , H. Zhu

This study identifies CXCR3-CXCL9/10 axis as a therapeutic target for ICI-mediated myocarditis using mouse models and human patient data.

bioRxiv · Jan 30, 2024 · PreprintCell Biology

AKT1 is Required for a Complete Palbociclib-induced Senescence Phenotype in BRAF-V600E-Driven Human Melanoma

A. L. Bayer, J. Pietruska, J. Farrell, S. McRee, P. Alcaide, P. W. Hinds

This study shows AKT1 is required for Palbociclib-induced senescence in BRAF-V600E melanoma cells, acting through NF-kB but not cGAS-STING.

bioRxiv · Dec 2, 2021Cancer Biology