S. Mitri

Environment-organism feedbacks drive changes in ecological interactions

The paper develops a theoretical framework to distinguish between external and organism-driven environmental changes in ecological interactions, using synthetic microbial communities to demonstrate its application.

The evolution of reduced facilitation in a four-species bacterial community

This study evolves four bacterial species in isolation and community to examine how positive interactions influence evolution, finding weakened interactions and resource specialization.

Artificial selection improves pollutant degradation by bacterial communities

This study shows that artificial selection of bacterial communities can improve pollutant degradation, with evolved communities outperforming initial ones.

Oxidative stress changes interactions between two bacterial species

This study shows that varying linoleic acid concentration changes the interaction between two bacterial species from competitive to facilitative, with one species reducing ROS to allow coexistence.

Novel artificial selection method improves function of simulated microbial communities

This paper introduces a new 'disassembly' method for simulating microbial community selection and finds it effectively explores species combinations but does not counteract individual-level selection or ecological dynamics.

Microbial invasion of a toxic medium is facilitated by a resident community but inhibited as the community co-evolves

The paper shows that microbial invaders can more easily colonize toxic environments with existing communities but face greater resistance when communities co-evolve.

Classifying interactions in a synthetic bacterial community is hindered by inhibitory growth medium

The paper identifies that inhibitory effects of growth media can confound interaction classification in synthetic bacterial communities and proposes guidelines to distinguish between cross-detoxification and cross-feeding.

An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer

This paper presents an OMS Atlas from serial biopsies of a metastatic breast cancer patient, linking clinical data to multi-omic and spatial profiles to study therapy-associated heterogeneity and resistance mechanisms.

Exclusion of the fittest predicts microbial community diversity in fluctuating environments

The paper models microbial community diversity under fluctuating environments, finding that extinction probabilities and beta diversity depend on switching rates and species resilience.

Controlling evolutionary dynamics to optimize microbial bioremediation

The paper models microbial bioremediation as an evolutionary game, showing how environmental parameters can control dynamics to optimize detoxification.

Toxicity drives facilitation between four bacterial species

The paper shows that toxicity in Metal-Working Fluids (MWF) drives positive interactions between four bacterial species by facilitating their survival and degradation of MWF.

Phage efficacy in infecting dual-strain biofilms of Pseudomonas aeruginosa

This study investigates how strain diversity in Pseudomonas aeruginosa biofilms affects phage efficacy, finding that spatial structure provides refuge and reduces resistance evolution.