Development of an antibody fused with an antimicrobial peptide targeting Pseudomonas aeruginosa: a new approach to prevent and treat bacterial infections
K. Johnson, J. Delaney, T. Guillard, F. Reffuveille, J. Varin-Simon, K. Li, A. Wollacott, E. Frapy, S. Mong, H. Tissire, K. Viswanathan, F. Touti, G. Babcock, Z. Shriver, B. Pentelute, , D. Skurnik
This paper develops an antibody-drug conjugate targeting Pseudomonas aeruginosa that kills bacteria with minimal mammalian cell toxicity and synergizes with antibiotics.
bioRxiv · Dec 28, 2022 · PreprintMicrobiology