Author

S. N. Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Claveras Cabezudo· 1 shared A. S. I. Cook· 1 shared A. T. Iavarone· 1 shared G. Hummer· 1 shared J. H. Hurley· 1 shared M. H. Chen· 1 shared S. Rao· 1 shared X. Ren· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. Claveras Cabezudo

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1 paper

Recent·Most cited

Structural pathway for class III PI 3-kinase activation by the myristoylated GTP-binding pseudokinase VPS15

A. S. I. Cook, M. H. Chen, X. Ren, S. Rao, S. N. Garcia, A. Claveras Cabezudo, A. T. Iavarone, G. Hummer, J. H. Hurley

This study maps the structural pathway of class III PI 3-kinase activation by showing how N-myristoylation of VPS15 stabilizes the inactive conformation and how GTP binding promotes activation.

bioRxiv · Sep 28, 2023Biochemistry