Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen
N. G. Bender, P. Khare, J. Martinez, R. E. Tweedell, V. O. Nyasembe, B. Lopez-Gutierrez, A. Tripathi, D. Miller, T. Hamerly, E. M. Vela, R. F. Howard, S. Nsango, R. R. Cobb, M. Harbers, R. R. Dinglasan
The paper evaluates a new malaria transmission-blocking vaccine antigen, UF6b, showing it induces potent antibodies against a key epitope and is immunogenic in mice.
bioRxiv · Nov 29, 2020Immunology